| عنوان فارسی مقاله: | رادیوتراپی سبب افزایش حساسیت سلول های توموری به اثرات ضدتوموری AD-MSCs (سلول های بنیادی مزانشیمال مشتق از چربی) فعال شده با TNF-α در مدل آزمایشگاهی سرطان سینه می شود |
| عنوان انگلیسی مقاله: | Irradiation enhances susceptibility of tumor cells to the antitumor effects of TNF-α activated adipose derived mesenchymal stem cells in breast cancer model |
چکیده
مقدمه
نتایج
بحث و گفت و گو
مواد و روش ها
موش و رده های سلولی توموری
ترکیبات و آنتی بادی ها
ریل تایم پی سی آر
کشت همزمان AD-MSCs و سلول های 4T1
فلوسیتومتری
بررسی های آماری
کلمات کلیدی :
A review of therapeutic effects of mesenchymal stem cell secretions ... https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-014-0260-8 by M Madrigal - 2014 - Cited by 56 - Related articles Oct 11, 2014 - Mesenchymal stem cells (MSCs) are classically defined as adherent, ... reconstitution in 28 breast cancer patients who received high dose chemotherapy with no .... activities in MSC is the macrophage-derived cytokine TNF-α. .... to be essential for the therapeutic effects of adipose derived MSCs in a rodent ... The roles of mesenchymal stem cells in tumor inflammatory ... https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-7-14 by Z Sun - 2014 - Cited by 67 - Related articles Feb 6, 2014 - Mesenchymal stem cell Tumor Inflammatory microenvironment ..... tissues and are therefore expected to produce anti-tumor effects. .... IFN-γ or TNF-α can enhance the immunosuppressive effects of MSCs [77, 78]. ... Exosomes derived from breast and ovarian cancer cells can cause adipose-derived MSCs ... TNF-α in Cancer Treatment: Molecular Insights, Antitumor Effects, and ... theoncologist.alphamedpress.org/content/11/4/397.full by R van Horssen - 2006 - Cited by 451 - Related articles Lower expression is known for a variety of other cells, including fibroblasts, ... Tumor necrosis factor alpha (TNF-α) activates both survival and proliferation ...... I (p55) is upregulated on endothelial cells by exposure to the tumour-derived cytokine .... Mesenchymal Stem Cells from Human Fat Engineered to Secrete BMP4 Are ... Irradiation enhances susceptibility of tumor cells to the ... - ReadCube www.readcube.com/articles/10.1038/srep28433 Gene modified or cytokine activated mesenchymal stem cells (MSCs) have been used ... promising anticancer proteins, increased in murine adipose-derived mesenchymal ... In vivo results showed that TNF-α preactivated AD-MSCs combined with ... with irradiation therapy can serve as new strategy in breast cancer therapy.