| عنوان فارسی مقاله: |
واکنش فعال سازی ترانس kDa-43 پاتولوژیکی پروتئین متصل به DNA در افراد مسن مبتلا به بیماری روانی سخت و بدون بیماری شدید روانی |
| عنوان انگلیسی مقاله: |
Pathological 43-kDa Transactivation Response DNA-Binding Protein in Older Adults With and Without Severe Mental Illness |
روشها
مطالعات موردی
بررسی ایمنوهیستوشیمی
ارزیابی پاتولوژی
آنالیز آماری
نتایج
یافته های میکروسکوپی TDP-43
پاتولوژی TDP-43 سابپایل /سابپندیمال
پاتولوژی TDP-43 کانونی
پاتولوژی TDP-43 پراکنده
پاتولوژی TDP-43 دور عروقی
یافته های ژنتیکی
همبستگی بالینی- پاتولوژیکی
توضیح
نتیجه گیریها
کلمات کلیدی :
Mental Illness: New Insights for the Healthcare Professional: 2011 ...https://books.google.com/books?isbn=146490832X2012 - MedicalAlthough the significance of pathological 43-kDa (transactivation response) DNA-binding protein (TDP-43) for frontotemporal lobar degeneration was ...Figure 1. Subpial or subependymal 43-kDa transactivation response...https://www.researchgate.net/.../47395748_fig1_Figure-1-Subpial-or-subependymal-43-...from publication 'Pathological 43-kDa Transactivation Response DNA-Binding Protein in Older Adults With and Without Severe Mental Illness' on ResearchGate ...Motor Neuron Disease, An Issue of Neurologic Clinics, E-Bookhttps://books.google.com/books?isbn=0323413455Richard J. Barohn - 2016 - MedicalMaturation process of TDP-43-positive neuronal cytoplasmic inclusions in ... Pathological 43-kDa transactivation response DNA-binding protein in older adults ...TAR DNA-binding protein 43, TDP-43 - Wikipediahttps://en.wikipedia.org/wiki/TARDBPTAR DNA-binding protein 43 is a protein that in humans is encoded by the TARDBP gene. ... Activation of HIV-1 gene expression by the transactivator "Tat" is dependent on an ... Cytoplasmic TDP-43 pathology is the dominant histopathological feature of ... "TDP43 is a human low molecular weight neurofilament (hNFL) ...Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein ...www.jbc.org/content/283/19/13302by MJ Winton - 2008 - Cited by 317 - Related articlesMay 9, 2008 - TAR DNA-binding protein 43 (TDP-43) is the disease protein in ... Although normal TDP-43 is a nuclear protein, pathological TDP-43 is ... Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by ..... Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein ...